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Aspartate-β-hydroxylase (ASPH): A potential therapeutic target in human malignant gliomas
BACKGROUND: Despite therapeutic advances, survival with glioblastoma multiforme (GBM) remains below 15 months from diagnosis due to GBM’s highly infiltrative nature which precludes complete surgical resection. Patient outcomes could potentially be improved by targeting genes and pathways that drive...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144823/ https://www.ncbi.nlm.nih.gov/pubmed/27981247 http://dx.doi.org/10.1016/j.heliyon.2016.e00203 |