A dividing matter: Drp1/Dnm1-independent mitophagy

Whether or not mitophagy depends on prior mitochondrial fragmentation by the canonical mitochondrial division machinery is controversial. In this issue, Yamashita et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201605093) report that mitochondrial fragments start to bud and divide from mitoc...

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Detalles Bibliográficos
Autor principal: Graef, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144889/
https://www.ncbi.nlm.nih.gov/pubmed/27903605
http://dx.doi.org/10.1083/jcb.201611079
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author Graef, Martin
author_facet Graef, Martin
author_sort Graef, Martin
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description Whether or not mitophagy depends on prior mitochondrial fragmentation by the canonical mitochondrial division machinery is controversial. In this issue, Yamashita et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201605093) report that mitochondrial fragments start to bud and divide from mitochondrial tubules when in tight association with forming autophagosomes, but independently of the mitochondrial division factor Drp1/Dnm1.
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spelling pubmed-51448892017-06-05 A dividing matter: Drp1/Dnm1-independent mitophagy Graef, Martin J Cell Biol Commentary Whether or not mitophagy depends on prior mitochondrial fragmentation by the canonical mitochondrial division machinery is controversial. In this issue, Yamashita et al. (2016. J. Cell Biol. https://doi.org/10.1083/jcb.201605093) report that mitochondrial fragments start to bud and divide from mitochondrial tubules when in tight association with forming autophagosomes, but independently of the mitochondrial division factor Drp1/Dnm1. The Rockefeller University Press 2016-12-05 /pmc/articles/PMC5144889/ /pubmed/27903605 http://dx.doi.org/10.1083/jcb.201611079 Text en © 2016 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Commentary
Graef, Martin
A dividing matter: Drp1/Dnm1-independent mitophagy
title A dividing matter: Drp1/Dnm1-independent mitophagy
title_full A dividing matter: Drp1/Dnm1-independent mitophagy
title_fullStr A dividing matter: Drp1/Dnm1-independent mitophagy
title_full_unstemmed A dividing matter: Drp1/Dnm1-independent mitophagy
title_short A dividing matter: Drp1/Dnm1-independent mitophagy
title_sort dividing matter: drp1/dnm1-independent mitophagy
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144889/
https://www.ncbi.nlm.nih.gov/pubmed/27903605
http://dx.doi.org/10.1083/jcb.201611079
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