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The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms
The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5 coordinates a complex network of effectors that functionally cooperate in membrane tethering, fusion, and or...
Autores principales: | Schnatwinkel, Carsten, Christoforidis, Savvas, Lindsay, Margaret R, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Parton, Robert G, Zerial, Marino |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514490/ https://www.ncbi.nlm.nih.gov/pubmed/15328530 http://dx.doi.org/10.1371/journal.pbio.0020261 |
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