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The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms

The small GTPase Rab5 is a key regulator of clathrin-mediated endocytosis. On early endosomes, within a spatially restricted domain enriched in phosphatydilinositol-3-phosphate [PI(3)P], Rab5 coordinates a complex network of effectors that functionally cooperate in membrane tethering, fusion, and or...

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Detalles Bibliográficos
Autores principales: Schnatwinkel, Carsten, Christoforidis, Savvas, Lindsay, Margaret R, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Parton, Robert G, Zerial, Marino
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514490/
https://www.ncbi.nlm.nih.gov/pubmed/15328530
http://dx.doi.org/10.1371/journal.pbio.0020261

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