Cargando…

TRPA1 in the spinal dorsal horn is involved in post-inflammatory visceral hypersensitivity: in vivo study using TNBS-treated rat model

INTRODUCTION: The transient receptor potential ankyrin-1 (TRPA1) channel, a pain transducer and amplifier, is drawing increasing attention in the field of visceral hypersensitivity, commonly seen in irritable bowel syndrome and inflammatory bowel disease. However, the role of TRPA1 in visceral nocic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qian, Guo, Cheng-Hao, Chowdhury, Mohammed Ali, Dai, Tao-Li, Han, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144908/ https://www.ncbi.nlm.nih.gov/pubmed/27980434 http://dx.doi.org/10.2147/JPR.S118581

Ejemplares similares

In vivo patch-clamp analysis of the antinociceptive actions of TRPA1 activation in the spinal dorsal horn
por: Yamanaka, Manabu, et al.
Publicado: (2015)

Study on the Mechanism Underlying the Regulation of the NMDA Receptor Pathway in Spinal Dorsal Horns of Visceral Hypersensitivity Rats by Moxibustion
por: Wang, L. D., et al.
Publicado: (2016)

Neonatal Colonic Inflammation Increases Spinal Transmission and Cystathionine β-Synthetase Expression in Spinal Dorsal Horn of Rats with Visceral Hypersensitivity
por: Zhao, Liting, et al.
Publicado: (2017)

Small-Conductance Ca(2+)-Activated K(+) Channel 2 in the Dorsal Horn of Spinal Cord Participates in Visceral Hypersensitivity in Rats
por: Song, Yu, et al.
Publicado: (2018)

Involvement of Brn3a-positive spinal dorsal horn neurons in the transmission of visceral pain in inflammatory bowel disease model mice
por: Nishida, Kazuhiko, et al.
Publicado: (2022)

Peripheral and Spinal Mechanisms Involved in Electro-Acupuncture Therapy for Visceral Hypersensitivity
por: Tahir, Adnan Hassan, et al.
Publicado: (2021)

Blockade of Erythropoietin-Producing Human Hepatocellular Carcinoma Receptor B1 in Spinal Dorsal Horn Alleviates Visceral Pain in Rats
por: Sun, Chen-Li, et al.
Publicado: (2021)

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy
por: Frezel, Noémie, et al.
Publicado: (2023)

Secondary damage and neuroinflammation in the spinal dorsal horn mediate post-thalamic hemorrhagic stroke pain hypersensitivity: SDF1-CXCR4 signaling mediation
por: Liang, Ting, et al.
Publicado: (2022)

Activation of spinal dorsal horn astrocytes by noxious stimuli involves descending noradrenergic signaling
por: Kawanabe, Riku, et al.
Publicado: (2021)

Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn
por: Chamessian, Alexander, et al.
Publicado: (2018)

Expression of cholecystokinin by neurons in mouse spinal dorsal horn
por: Gutierrez‐Mecinas, Maria, et al.
Publicado: (2019)

Elevated serotonin in mouse spinal dorsal horn is pronociceptive
por: Cramer, Nathan, et al.
Publicado: (2023)

Altered sympathovagal balance and pain hypersensitivity in TNBS-induced colitis
por: Ciesielczyk, Katarzyna, et al.
Publicado: (2016)

Spinal TRPA1 Contributes to the Mechanical Hypersensitivity Effect Induced by Netrin-1
por: Wei, Hong, et al.
Publicado: (2022)

Neurotoxicity of intrathecal injections of dexmedetomidine into the rat spinal dorsal horn★
por: Hou, Jiabao, et al.
Publicado: (2012)

Aging alters signaling properties in the mouse spinal dorsal horn
por: Mayhew, JA, et al.
Publicado: (2019)

Dorsal Horn of Mouse Lumbar Spinal Cord Imaged with CLARITY
por: Sengul, Gulgun, et al.
Publicado: (2020)

Serotonergic Modulation of Nociceptive Circuits in Spinal Cord Dorsal Horn
por: Bardoni, Rita
Publicado: (2019)

Ionotropic Glutamate Receptors and Voltage-Gated Ca(2+) Channels in Long-Term Potentiation of Spinal Dorsal Horn Synapses and Pain Hypersensitivity
por: Youn, Dong-ho, et al.
Publicado: (2013)

Targeted up-regulation of Drp1 in dorsal horn attenuates neuropathic pain hypersensitivity by increasing mitochondrial fission
por: Zhang, Kun-Long, et al.
Publicado: (2021)

Noradrenaline modulates mechanically evoked responses in the rat spinal dorsal horn: an in vivo patch-clamp study
por: Sonohata, Motoki, et al.
Publicado: (2019)

Proteomic Analysis of the Spinal Dorsal Horn in Mice with Neuropathic Pain After Exercise
por: Bai, Jie, et al.
Publicado: (2023)

Effects of TRPA1 activation and inhibition on TRPA1 and CGRP expression in dorsal root ganglion neurons
por: Wang, Xiao-Lei, et al.
Publicado: (2019)

Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes
por: Zhang, Haijun, et al.
Publicado: (2009)

Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn
por: Labrakakis, Charalampos, et al.
Publicado: (2009)

Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses
por: Meneses, Constanza Stefania, et al.
Publicado: (2017)

Peripheral and spinal TRPA1 channels contribute to formalin-induced long-lasting mechanical hypersensitivity
por: Martínez-Rojas, Vladimir A, et al.
Publicado: (2017)

Neurexin‐2 is a potential regulator of inflammatory pain in the spinal dorsal horn of rats
por: Xu, Longsheng, et al.
Publicado: (2020)

Morphological investigations of endomorphin-2 and spinoparabrachial projection neurons in the spinal dorsal horn of the rat
por: Yin, Jun-Bin, et al.
Publicado: (2022)

Stereological Study of Changes of GABA-Immunoreactive Neurons in Spinal Dorsal Horn of SNI Rats
por: Liu, Hong, et al.
Publicado: (2021)

Electroacupuncture intervention of visceral hypersensitivity is involved in PAR-2-activation and CGRP-release in the spinal cord
por: Shah, Manoj K., et al.
Publicado: (2020)

Inward currents induced by ischemia in rat spinal cord dorsal horn neurons
por: Chen, Meng, et al.
Publicado: (2007)

Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP
por: Bird, Gary C, et al.
Publicado: (2006)

Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord
por: Kardon, Adam P., et al.
Publicado: (2014)

Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal horn
por: Punnakkal, Pradeep, et al.
Publicado: (2014)

Tranexamic acid evokes pain by modulating neuronal excitability in the spinal dorsal horn
por: Ohashi, Nobuko, et al.
Publicado: (2015)

A new minimally-invasive method for microinjection into the mouse spinal dorsal horn
por: Kohro, Yuta, et al.
Publicado: (2015)

The effect of µ-opioid receptor activation on GABAergic neurons in the spinal dorsal horn
por: Kim, Yoo Rim, et al.
Publicado: (2018)

Insights Into Spinal Dorsal Horn Circuit Function and Dysfunction Using Optical Approaches
por: Harding, Erika K., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_unfee45irm0jleej4devcpsfbr