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Sir2-Independent Life Span Extension by Calorie Restriction in Yeast
Calorie restriction slows aging and increases life span in many organisms. In yeast, a mechanistic explanation has been proposed whereby calorie restriction slows aging by activating Sir2. Here we report the identification of a Sir2-independent pathway responsible for a majority of the longevity ben...
Autores principales: | Kaeberlein, Matt, Kirkland, Kathryn T, Fields, Stanley, Kennedy, Brian K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514491/ https://www.ncbi.nlm.nih.gov/pubmed/15328540 http://dx.doi.org/10.1371/journal.pbio.0020296 |
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