Cluster of human parechovirus infections as the predominant cause of sepsis in neonates and infants, Leicester, United Kingdom, 8 May to 2 August 2016

We report an unusually high number of cases (n = 26) of parechovirus infections in the cerebrospinal fluid (CSF) of neonates and infants admitted with sepsis in the United Kingdom during 8 May to 2 August 2016. Although such infections in neonates and infants are well-documented, parechovirus has no...

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Detalles Bibliográficos
Autores principales: Tang, Julian W, Holmes, Christopher W, Elsanousi, Fadwa A, Patel, Ayushi, Adam, Fazila, Speight, Rachel, Shenoy, Savitha, Bronnert, Daniel, Stiefel, Gary, Sundaram, Premkumar, Pande, Suchandra, Sridhar, Arani, Kairamkonda, Venkatesh, Bandi, Srini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2016
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144936/
https://www.ncbi.nlm.nih.gov/pubmed/27589339
http://dx.doi.org/10.2807/1560-7917.ES.2016.21.34.30326
Descripción
Sumario:We report an unusually high number of cases (n = 26) of parechovirus infections in the cerebrospinal fluid (CSF) of neonates and infants admitted with sepsis in the United Kingdom during 8 May to 2 August 2016. Although such infections in neonates and infants are well-documented, parechovirus has not been routinely included in many in-house and commercial PCR assays for CSF testing. Clinicians should consider routine parechovirus testing in young children presenting with sepsis.

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