Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection

Multi-parent populations (MPPs) capture and maintain the genetic diversity from multiple inbred founder strains to provide a resource for high-resolution genetic mapping through the accumulation of recombination events over many generations. Breeding designs that maintain a large effective populatio...

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Detalles Bibliográficos
Autores principales: Chesler, Elissa J., Gatti, Daniel M., Morgan, Andrew P., Strobel, Marge, Trepanier, Laura, Oberbeck, Denesa, McWeeney, Shannon, Hitzemann, Robert, Ferris, Martin, McMullan, Rachel, Clayshultle, Amelia, Bell, Timothy A., de Villena, Fernando Pardo-Manuel, Churchill, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Multiparental Populations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144960/
https://www.ncbi.nlm.nih.gov/pubmed/27694113
http://dx.doi.org/10.1534/g3.116.035527

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