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A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings
Most mutant alleles in the Fz-PCP pathway genes were discovered in classic Drosophila screens looking for recessive loss-of-function (LOF) mutations. Nonetheless, although Fz-PCP signaling is sensitive to increased doses of PCP gene products, not many screens have been performed in the wing under ge...
Autores principales: | Carvajal-Gonzalez, Jose Maria, Mulero-Navarro, Sonia, Smith, Michael, Mlodzik, Marek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5144966/ https://www.ncbi.nlm.nih.gov/pubmed/27729438 http://dx.doi.org/10.1534/g3.116.035535 |
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