Perinatal Natural History of the Ts1Cje Mouse Model of Down Syndrome: Growth Restriction, Early Mortality, Heart Defects, and Delayed Development

BACKGROUND: The Ts1Cje model of Down syndrome is of particular interest for perinatal studies because affected males are fertile. This permits affected pups to be carried in wild-type females, which is similar to human pregnancies. Here we describe the early natural history and growth profiles of Ts...

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Detalles Bibliográficos
Autores principales: Ferrés, Millie A., Bianchi, Diana W., Siegel, Ashley E., Bronson, Roderick T., Huggins, Gordon S., Guedj, Faycal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145234/
https://www.ncbi.nlm.nih.gov/pubmed/27930746
http://dx.doi.org/10.1371/journal.pone.0168009

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