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Resolution of mitochondrial oxidant stress improves aged-cardiovascular performance

BACKGROUND: Senescence is a major factor that increases oxidative stress in mitochondria, which contributes toward the pathogenesis of heart disease. However, the effect of antioxidant therapy on cardiac mitochondria in aged-cardiac performance remains elusive. OBJECTIVES: We postulated that the mit...

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Detalles Bibliográficos
Autores principales: Owada, Takashi, Yamauchi, Hiroyuki, Saitoh, Shu-ichi, Miura, Shunsuke, Machii, Hirofumi, Takeishi, Yasuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145249/
https://www.ncbi.nlm.nih.gov/pubmed/27740971
http://dx.doi.org/10.1097/MCA.0000000000000434