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Loss of Skeletal Muscle HIF-1α Results in Altered Exercise Endurance
The physiological flux of oxygen is extreme in exercising skeletal muscle. Hypoxia is thus a critical parameter in muscle function, influencing production of ATP, utilization of energy-producing substrates, and manufacture of exhaustion-inducing metabolites. Glycolysis is the central source of anaer...
Autores principales: | Mason, Steven D, Howlett, Richard A, Kim, Matthew J, Olfert, I. Mark, Hogan, Michael C, McNulty, Wayne, Hickey, Reed P, Wagner, Peter D, Kahn, C. Ronald, Giordano, Frank J, Johnson, Randall S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514537/ https://www.ncbi.nlm.nih.gov/pubmed/15328538 http://dx.doi.org/10.1371/journal.pbio.0020288 |
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