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Attenuation of dengue virus infection by adeno-associated virus-mediated siRNA delivery

BACKGROUND: The need for safe and effective treatment of dengue virus (DEN), a class A agent that causes dengue hemorrhagic fever/dengue shock syndrome, has been a critical global priority. An effective vaccine for DEN is not yet available. In this study the possibility of attenuating DEN infection...

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Detalles Bibliográficos
Autores principales: Zhang, Weidong, Singam, Rajeswari, Hellermann, Gary, Kong, Xiaoyuan, Juan, Homero San, Lockey, Richard F, Wu, Shuen-Ju, Porter, Kevin, Mohapatra, Shyam S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514572/
https://www.ncbi.nlm.nih.gov/pubmed/15301687
http://dx.doi.org/10.1186/1479-0556-2-8