Cargando…

Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1

Endosomal sorting complexes required for transport (ESCRTs) are essential for ubiquitin-dependent degradation of mitogenic receptors, a process often compromised in cancer pathologies. Sorting of ubiquinated receptors via ESCRTs is controlled by the tumor suppressor phosphatase HD-PTP. The specific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gahloth, Deepankar, Levy, Colin, Heaven, Graham, Stefani, Flavia, Wunderley, Lydia, Mould, Paul, Cliff, Matthew J., Bella, Jordi, Fielding, Alistair J., Woodman, Philip, Tabernero, Lydia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145805/ https://www.ncbi.nlm.nih.gov/pubmed/27839950 http://dx.doi.org/10.1016/j.str.2016.10.006

Ejemplares similares

The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function
por: Gahloth, Deepankar, et al.
Publicado: (2017)

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP
por: Gahloth, Deepankar, et al.
Publicado: (2017)

The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex
por: Wunderley, Lydia, et al.
Publicado: (2014)

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes
por: Kazan, Jalal M., et al.
Publicado: (2021)

Dissecting the role of His domain protein tyrosine phosphatase/PTPN23 and ESCRTs in sorting activated epidermal growth factor receptor to the multivesicular body
por: Tabernero, Lydia, et al.
Publicado: (2018)

A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors
por: Imbert, Paul RC, et al.
Publicado: (2017)

The UBAP1 Subunit of ESCRT-I Interacts with Ubiquitin via a SOUBA Domain
por: Agromayor, Monica, et al.
Publicado: (2012)

Spin Labeling of Surface Cysteines Using a Bromoacrylaldehyde Spin Label
por: Heaven, Graham, et al.
Publicado: (2021)

Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme
por: Egbe, Eyong, et al.
Publicado: (2020)

Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0
por: Lee, Juhyeon, et al.
Publicado: (2016)

Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX
por: Shirasaki, Takayoshi, et al.
Publicado: (2022)

A non-canonical ESCRT pathway, including histidine domain phosphotyrosine phosphatase (HD-PTP), is used for down-regulation of virally ubiquitinated MHC class I
por: Parkinson, Michael D.J., et al.
Publicado: (2015)

Structural and biochemical characterization of the prenylated flavin mononucleotide-dependent indole-3-carboxylic acid decarboxylase
por: Gahloth, Deepankar, et al.
Publicado: (2022)

A New Paradigm for KIM-PTP Drug Discovery: Identification of Allosteric Sites with Potential for Selective Inhibition Using Virtual Screening and LEI Analysis
por: Adams, James, et al.
Publicado: (2021)

Protein tyrosine phosphatase TbPTP1: a molecular switch controlling life cycle differentiation in trypanosomes
por: Szöőr, Balázs, et al.
Publicado: (2006)

The Charcot Marie Tooth disease protein LITAF is a zinc-binding monotopic membrane protein
por: Qin, Wenxia, et al.
Publicado: (2016)

Endosomal recycling tubule scission and integrin recycling involve the membrane curvature-supporting protein LITAF
por: Wunderley, Lydia, et al.
Publicado: (2021)

Structural Basis for ESCRT-III Protein Autoinhibition
por: Bajorek, Monika, et al.
Publicado: (2009)

ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage
por: Willan, Jessica, et al.
Publicado: (2019)

Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis
por: Seong, Chang-Soo, et al.
Publicado: (2023)

ESCRT-0 marks an APPL1-independent transit route for EGFR between the cell surface and the EEA1-positive early endosome
por: Flores-Rodriguez, Neftali, et al.
Publicado: (2015)

HD-PTP Is a Catalytically Inactive Tyrosine Phosphatase Due to a Conserved Divergence in Its Phosphatase Domain
por: Gingras, Marie-Claude, et al.
Publicado: (2009)

The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization
por: Husedzinovic, Alma, et al.
Publicado: (2015)

Interactions of ubiquitin and CHMP5 with the V domain of HD-PTP reveals role for regulation of Vps4 ATPase
por: Pashkova, Natalya, et al.
Publicado: (2021)

Ubap1 knock-in mice reproduced the phenotype of SPG80
por: Shimozono, Keisuke, et al.
Publicado: (2022)

Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs
por: Fernandez-Soto, Paulina, et al.
Publicado: (2019)

SGTA regulates the cytosolic quality control of hydrophobic substrates
por: Wunderley, Lydia, et al.
Publicado: (2014)

Constitutively active ESCRT-II suppresses the MVB-sorting phenotype of ESCRT-0 and ESCRT-I mutants
por: Mageswaran, Shrawan Kumar, et al.
Publicado: (2015)

The ESCRT machinery
por: Schmidt, Oliver, et al.
Publicado: (2012)

Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation
por: Lin, Zhaohan, et al.
Publicado: (2018)

Two novel truncating variants in UBAP1 are responsible for hereditary spastic paraplegia
por: Bian, Xinchao, et al.
Publicado: (2021)

Dynamic Association of ESCRT-II Proteins with ESCRT-I and ESCRT-III Complexes during Phagocytosis of Entamoeba histolytica
por: Díaz-Hernández, Mitzi, et al.
Publicado: (2023)

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B
por: Yang, Dong, et al.
Publicado: (2008)

Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments
por: Tang, Shaogeng, et al.
Publicado: (2015)

The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cellular collapse and spinal motor axon guidance
por: Lahaie, Sylvie, et al.
Publicado: (2019)

Characterization of a Putrescine Transaminase From Pseudomonas putida and its Application to the Synthesis of Benzylamine Derivatives
por: Galman, James L., et al.
Publicado: (2018)

ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis
por: Tang, Shaogeng, et al.
Publicado: (2016)

Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ
por: Karki, Sudeep, et al.
Publicado: (2020)

UBAP2L arginine methylation by PRMT1 modulates stress granule assembly
por: Huang, Chuyu, et al.
Publicado: (2019)

UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis
por: Guerber, Lucile, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_m7vu670jcpsct58bralf6v9rl2