A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling

Central to homologous recombination in eukaryotes is the RAD51 recombinase, which forms helical nucleoprotein filaments on single-stranded DNA (ssDNA) and catalyzes strand invasion with homologous duplex DNA. Various regulatory proteins assist this reaction including the RAD51 paralogs. We recently...

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Detalles Bibliográficos
Autores principales: Taylor, Martin R.G., Špírek, Mário, Jian Ma, Chu, Carzaniga, Raffaella, Takaki, Tohru, Collinson, Lucy M., Greene, Eric C., Krejci, Lumir, Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145814/
https://www.ncbi.nlm.nih.gov/pubmed/27867009
http://dx.doi.org/10.1016/j.molcel.2016.10.020

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