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Enzyme-Mediated Quenching of the Pseudomonas Quinolone Signal (PQS) Promotes Biofilm Formation of Pseudomonas aeruginosa by Increasing Iron Availability

The 2-alkyl-3-hydroxy-4(1H)-quinolone 2,4-dioxygenase HodC was previously described to cleave the Pseudomonas quinolone signal, PQS, which is exclusively used in the complex quorum sensing (QS) system of Pseudomonas aeruginosa, an opportunistic pathogen employing QS to regulate virulence and biofilm...

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Detalles Bibliográficos
Autores principales:	Tettmann, Beatrix, Niewerth, Christine, Kirschhöfer, Frank, Neidig, Anke, Dötsch, Andreas, Brenner-Weiss, Gerald, Fetzner, Susanne, Overhage, Joerg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145850/ https://www.ncbi.nlm.nih.gov/pubmed/28018312 http://dx.doi.org/10.3389/fmicb.2016.01978

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