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PD-L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN-γ and Can Be Expressed in the Tumor Microenvironment
The devil facial tumor disease (DFTD) is caused by clonal transmissible cancers that have led to a catastrophic decline in the wild Tasmanian devil (Sarcophilus harrisii) population. The first transmissible tumor, now termed devil facial tumor 1 (DFT1), was first discovered in 1996 and has been cont...
Autores principales: | Flies, Andrew S., Lyons, A. Bruce, Corcoran, Lynn M., Papenfuss, Anthony T., Murphy, James M., Knowles, Graeme W., Woods, Gregory M., Hayball, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145852/ https://www.ncbi.nlm.nih.gov/pubmed/28018348 http://dx.doi.org/10.3389/fimmu.2016.00581 |
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