Cargando…

Low Double-Negative CD3(+)CD4(−)CD8(−) T Cells Are Associated with Incomplete Restoration of CD4(+) T Cells and Higher Immune Activation in HIV-1 Immunological Non-Responders

Failure of immune reconstitution increases the risk of AIDS or non-AIDS related morbidity and mortality in HIV-1-infected patients. CD3(+)CD4(−)CD8(−) T cells, which are usually described as double-negative (DN) T cells, display CD4-like helper and immunoregulatory functions. Here, we have measured...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Xiaofan, Su, Bin, Xia, Huan, Zhang, Xin, Liu, Zhiying, Ji, Yunxia, Yang, Zixuan, Dai, Lili, Mayr, Luzia M., Moog, Christiane, Wu, Hao, Huang, Xiaojie, Zhang, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145861/ https://www.ncbi.nlm.nih.gov/pubmed/28018346 http://dx.doi.org/10.3389/fimmu.2016.00579

Ejemplares similares

Increased early activation of CD56(dim)CD16(dim/-) natural killer cells in immunological non-responders correlates with CD4(+) T-cell recovery
por: Zhang, Qiu-Yue, et al.
Publicado: (2020)

Persistent T cell proliferation and MDSCs expansion precede incomplete CD4(+) T cell recovery in people with acute HIV-1 infection with early ART
por: Li, Zhen, et al.
Publicado: (2023)

Regulation of CD4(+)CD8(−)CD25(+) and CD4(+)CD8(+)CD25(+) T cells by gut microbiota in chicken
por: Lee, In Kyu, et al.
Publicado: (2018)

T cells that cannot respond to TGF-β escape control by CD4(+)CD25(+) regulatory T cells
por: Fahlén, Linda, et al.
Publicado: (2005)

Failure of CD4 T-Cells to Respond to Liver-Derived Antigen and to Provide Help to CD8 T-Cells
por: Derkow, Katja, et al.
Publicado: (2011)

Human CD4 restores normal T cell development and function in mice deficient in murine CD4
Publicado: (1994)

Immunology repertoire study of pulmonary sarcoidosis T cells in CD4+, CD8+ PBMC and tissue
por: Fu, Yingyun, et al.
Publicado: (2017)

Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells
por: Dalton, Dyana K., et al.
Publicado: (2000)

Percentages of CD4+CD161+ and CD4−CD8−CD161+ T Cells in the Synovial Fluid Are Correlated with Disease Activity in Rheumatoid Arthritis
por: Miao, Jinlin, et al.
Publicado: (2015)

Clonal Structure of Rapid-Onset MDV-Driven CD4+ Lymphomas and Responding CD8+ T Cells
por: Mwangi, William N., et al.
Publicado: (2011)

Long terms trends in CD4(+) cell counts, CD8(+) cell counts, and the CD4(+) : CD8(+) ratio
por: Hughes, Rachael A., et al.
Publicado: (2018)

CD4(+) and CD8(+) T Cell Activation Are Associated with HIV DNA in Resting CD4(+) T Cells
por: Cockerham, Leslie R., et al.
Publicado: (2014)

CD4(+) T cells support polyfunctionality of cytotoxic CD8(+) T cells with memory potential in immunological control of tumor
por: Imai, Naoko, et al.
Publicado: (2020)

Changes in Reactivity In Vitro of CD4(+)CD25(+) and CD4(+)CD25(−) T Cell Subsets in Transplant Tolerance
por: Hall, Bruce M., et al.
Publicado: (2017)

Role of CD4(+)T, CD8(+)T Cells, and CD4(+)T/CD8(+)T Cell Ratio in Gastric Cancer and Its Clinical Significance
por: Han, Jingqi, et al.
Publicado: (2022)

The Many Faces of CD4(+) T Cells: Immunological and Structural Characteristics
por: Chatzileontiadou, Demetra S. M., et al.
Publicado: (2020)

Immunological features beyond CD4/CD8 ratio values in older individuals
por: Garrido-Rodríguez, Vanesa, et al.
Publicado: (2021)

CD160 isoforms and regulation of CD4 and CD8 T-cell responses
por: El-Far, Mohamed, et al.
Publicado: (2014)

CD32 is enriched on CD4(dim)CD8(bright) T cells
por: Virdi, Amber K., et al.
Publicado: (2020)

In Vivo Dynamical Interactions between CD4 Tregs, CD8 Tregs and CD4(+)CD25(−) Cells in Mice
por: Arazi, Arnon, et al.
Publicado: (2009)

Visualization of CD4/CD8 T Cell Commitment
por: Chan, Susan, et al.
Publicado: (1998)

CD4+ but not CD8+ cells are essential for allorejection
Publicado: (1996)

Conversion of the CD8 lineage to CD4 T cells
por: Guzman, Maria P., et al.
Publicado: (2015)

CD3(+)T, CD4(+)T, CD8(+)T, and CD4(+)T/CD8(+)T Ratio and Quantity of γδT Cells in Peripheral Blood of HIV-Infected/AIDS Patients and Its Clinical Significance
por: Zhao, Nange, et al.
Publicado: (2021)

CD4/CD8/Dendritic cell complexes in the spleen: CD8(+) T cells can directly bind CD4(+) T cells and modulate their response
por: Barinov, Aleksandr, et al.
Publicado: (2017)

Conversion of CD4(+) CD25(−) cells into CD4(+) CD25(+) regulatory T cells in vivo requires B7 costimulation, but not the thymus
por: Liang, Shuang, et al.
Publicado: (2005)

Retracted: Role of CD4(+)T, CD8(+)T Cells, and CD4(+)T/CD8(+)T Cell Ratio in Gastric Cancer and Its Clinical Significance
por: and Biomechanics, Applied Bionics
Publicado: (2023)

Dendritic cell–expanded, islet-specific CD4(+) CD25(+) CD62L(+) regulatory T cells restore normoglycemia in diabetic NOD mice
por: Tarbell, Kristin V., et al.
Publicado: (2007)

Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes
por: Lin, Ying-zhong, et al.
Publicado: (2013)

The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial
por: Somsouk, Ma, et al.
Publicado: (2014)

Decreased CD127 Expression on CD4+ T-Cells and Elevated Frequencies of CD4+CD25+CD127− T-Cells in Children with Long-Lasting Type 1 Diabetes
por: Moniuszko, Marcin, et al.
Publicado: (2013)

Regulatory CD4(+)CD25(+) T Cells Restrict Memory CD8(+) T Cell Responses
por: Kursar, Mischo, et al.
Publicado: (2002)

CD8 is required during positive selection of CD4-/CD8+ T cells
Publicado: (1990)

Transcriptional signatures of Itk-deficient CD3(+), CD4(+ )and CD8(+ )T-cells
por: Blomberg, K Emelie M, et al.
Publicado: (2009)

Expression of intrahepatic CD3, CD4, and CD8 T cells in biliary atresia
por: Behairy, Behairy E., et al.
Publicado: (2017)

Association between CD4(+) T cell counts and gut microbiota and serum cytokines levels in HIV-infected immunological non-responders
por: Lu, Danfeng, et al.
Publicado: (2021)

Immunologic Self-Tolerance Maintained by Cd25(+)Cd4(+)Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
por: Takahashi, Takeshi, et al.
Publicado: (2000)

CD3, CD4, CD8, CD19 and CD16/CD56 positive cells in tuberculosis infection and disease: Peculiar features in children
por: Venturini, Elisabetta, et al.
Publicado: (2019)

Immunological predictors of CD4(+ )T cell decline in antiretroviral treatment interruptions
por: Seoane, Elena, et al.
Publicado: (2008)

CD4 T Helper Cell Subsets and Related Human Immunological Disorders
por: Zhu, Xiaoliang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8j7fdnh8769m27n2p3q93og039