A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats

BACKGROUND: Gabapentin and pregabalin have wide-ranging therapeutic actions, and are structurally related to the inhibitory neurotransmitter GABA. Gabapentin, pregablin and GABA can all modulate voltage-activated Ca(2+ )channels. In this study we have used whole cell patch clamp recording and fura-2...

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Detalles Bibliográficos
Autores principales: McClelland, David, Evans, Rhian M, Barkworth, Louise, Martin, Duncan J, Scott, Roderick H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514605/
https://www.ncbi.nlm.nih.gov/pubmed/15294026
http://dx.doi.org/10.1186/1471-2210-4-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514605/
https://www.ncbi.nlm.nih.gov/pubmed/15294026
http://dx.doi.org/10.1186/1471-2210-4-14

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