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A study comparing the actions of gabapentin and pregabalin on the electrophysiological properties of cultured DRG neurones from neonatal rats

BACKGROUND: Gabapentin and pregabalin have wide-ranging therapeutic actions, and are structurally related to the inhibitory neurotransmitter GABA. Gabapentin, pregablin and GABA can all modulate voltage-activated Ca(2+ )channels. In this study we have used whole cell patch clamp recording and fura-2...

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Detalles Bibliográficos
Autores principales:	McClelland, David, Evans, Rhian M, Barkworth, Louise, Martin, Duncan J, Scott, Roderick H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2004
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514605/ https://www.ncbi.nlm.nih.gov/pubmed/15294026 http://dx.doi.org/10.1186/1471-2210-4-14

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