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Pioglitazone, a PPARγ agonist rescues depression associated with obesity using chronic unpredictable mild stress model in experimental mice

Pioglitazone, a peroxisome proliferator activated receptor gamma (PPARγ) agonist belonging to thiazolidinedione class, is mainly used in diabetes mellitus. Obese subjects are twice likely to become depressed than non-obese individuals. The biological mechanisms linking depression with obesity still...

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Detalles Bibliográficos
Autores principales: Kurhe, Yeshwant, Mahesh, Radhakrishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146196/
https://www.ncbi.nlm.nih.gov/pubmed/27981184
http://dx.doi.org/10.1016/j.ynstr.2016.05.001