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Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders
The recent identification of multiple new genetic causes of neurological disorders highlights the need for model systems that give experimental access to the underlying biology. In particular, the ability to couple disease-causing mutations with human neuronal differentiation systems would be benefi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146642/ https://www.ncbi.nlm.nih.gov/pubmed/27976757 http://dx.doi.org/10.12688/wellcomeopenres.10011.1 |