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Dissecting the Interplay Between Intestinal Microbiota and Host Immunity in Health and Disease: Lessons Learned from Germfree and Gnotobiotic Animal Models
This review elaborates the development of germfree and gnotobiotic animal models and their application in the scientific field to unravel mechanisms underlying host–microbe interactions and distinct diseases. Strictly germfree animals are raised in isolators and not colonized by any organism at all....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Akadémiai Kiadó
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146645/ https://www.ncbi.nlm.nih.gov/pubmed/27980855 http://dx.doi.org/10.1556/1886.2016.00036 |