BIX01294, an inhibitor of histone methyltransferase, induces autophagy-dependent differentiation of glioma stem-like cells

Glioblastoma (GBM) contains rare glioma stem-like cells (GSCs) with capacities of self-renewal, multi-lineage differentiation, and resistance to conventional therapy. Drug-induced differentiation of GSCs is recognized as a promising approach of anti-glioma therapy. Accumulating evidence suggests tha...

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Detalles Bibliográficos
Autores principales: Ciechomska, Iwona Anna, Przanowski, Piotr, Jackl, Judyta, Wojtas, Bartosz, Kaminska, Bozena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146656/
https://www.ncbi.nlm.nih.gov/pubmed/27934912
http://dx.doi.org/10.1038/srep38723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146656/
https://www.ncbi.nlm.nih.gov/pubmed/27934912
http://dx.doi.org/10.1038/srep38723

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