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Successful application of virtual screening and molecular dynamics simulations against antimalarial molecular targets
The main challenge in the control of malaria has been the emergence of drug-resistant parasites. The presence of drug-resistant Plasmodium sp. has raised the need for new antimalarial drugs. Molecular modelling techniques have been used as tools to develop new drugs. In this study, we employed virtu...
Autores principales: | Nunes, Renata Rachide, Costa, Marina dos Santos, Santos, Bianca dos Reis, da Fonseca, Amanda Luisa, Ferreira, Lorena Sales, Chagas, Rafael Cesar Russo, da Silva, Alisson Marques, Varotti, Fernando de Pilla, Taranto, Alex Gutterres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146734/ https://www.ncbi.nlm.nih.gov/pubmed/27982302 http://dx.doi.org/10.1590/0074-02760160207 |
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