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LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways

BACKGROUND: Neuroinflammation is characterized by microglial activation and the increased levels of cytokines and chemokines in the central nervous system (CNS). Recent evidence has implicated both beneficial and toxic roles of microglia when over-activated upon nerve injury or in neurodegenerative...

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Detalles Bibliográficos
Autores principales: Yang, Longyu, Liu, Chia-Chen, Zheng, Honghua, Kanekiyo, Takahisa, Atagi, Yuka, Jia, Lin, Wang, Daxin, N’songo, Aurelie, Can, Dan, Xu, Huaxi, Chen, Xiao-Fen, Bu, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146875/
https://www.ncbi.nlm.nih.gov/pubmed/27931217
http://dx.doi.org/10.1186/s12974-016-0772-7