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LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways
BACKGROUND: Neuroinflammation is characterized by microglial activation and the increased levels of cytokines and chemokines in the central nervous system (CNS). Recent evidence has implicated both beneficial and toxic roles of microglia when over-activated upon nerve injury or in neurodegenerative...
Autores principales: | Yang, Longyu, Liu, Chia-Chen, Zheng, Honghua, Kanekiyo, Takahisa, Atagi, Yuka, Jia, Lin, Wang, Daxin, N’songo, Aurelie, Can, Dan, Xu, Huaxi, Chen, Xiao-Fen, Bu, Guojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146875/ https://www.ncbi.nlm.nih.gov/pubmed/27931217 http://dx.doi.org/10.1186/s12974-016-0772-7 |
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