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Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts

BACKGROUND: Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility. Non-esterified fatty acids (NEFA) are involved in this pathogenesis as they jeopardize oocyte and embryo development. Growing evidence in...

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Detalles Bibliográficos
Autores principales: Desmet, K. L. J, Van Hoeck, V., Gagné, D., Fournier, E., Thakur, A., O’Doherty, A. M., Walsh, C. P., Sirard, M. A., Bols, P. E. J., Leroy, J. L. M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146907/
https://www.ncbi.nlm.nih.gov/pubmed/27931182
http://dx.doi.org/10.1186/s12864-016-3366-y