Increasing the Chemical‐Shift Dispersion of Unstructured Proteins with a Covalent Lanthanide Shift Reagent

The study of intrinsically disordered proteins (IDPs) by NMR often suffers from highly overlapped resonances that prevent unambiguous chemical‐shift assignments, and data analysis that relies on well‐separated resonances. We present a covalent paramagnetic lanthanide‐binding tag (LBT) for increasing...

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Detalles Bibliográficos
Autores principales: Göbl, Christoph, Resch, Moritz, Strickland, Madeleine, Hartlmüller, Christoph, Viertler, Martin, Tjandra, Nico, Madl, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146990/
https://www.ncbi.nlm.nih.gov/pubmed/27763708
http://dx.doi.org/10.1002/anie.201607261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5146990/
https://www.ncbi.nlm.nih.gov/pubmed/27763708
http://dx.doi.org/10.1002/anie.201607261

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