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A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) can be shed from the cell membrane by GPI cleavage. In this study, we report a novel GPI-processing enzyme, termed post-glycosylphosphatidylinositol attachment to proteins 6 (PGAP6), which is a GPI-specific phospholipase A2 mainly localized at...
Autores principales: | Lee, Gun-Hee, Fujita, Morihisa, Takaoka, Katsuyoshi, Murakami, Yoshiko, Fujihara, Yoshitaka, Kanzawa, Noriyuki, Murakami, Kei-ichi, Kajikawa, Eriko, Takada, Yoko, Saito, Kazunobu, Ikawa, Masahito, Hamada, Hiroshi, Maeda, Yusuke, Kinoshita, Taroh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147002/ https://www.ncbi.nlm.nih.gov/pubmed/27881714 http://dx.doi.org/10.1083/jcb.201605121 |
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