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Identification of proteases employed by dendritic cells in the processing of protein purified derivative (PPD)

Dendritic cells (DC) are known to present exogenous protein Ag effectively to T cells. In this study we sought to identify the proteases that DC employ during antigen processing. The murine epidermal-derived DC line Xs52, when pulsed with PPD, optimally activated the PPD-reactive Th1 clone LNC.2F1 a...

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Detalles Bibliográficos
Autores principales: Mohamadzadeh, Mansour, Mohamadzadeh, Hamid, Brammer, Melissa, Sestak, Karol, Luftig, Ronald B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514720/
https://www.ncbi.nlm.nih.gov/pubmed/15287985
http://dx.doi.org/10.1186/1476-8518-2-8