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Using hyaluronic acid-functionalized pH stimuli-responsive mesoporous silica nanoparticles for targeted delivery to CD44-overexpressing cancer cells

In this study, novel hyaluronic acid-pH stimuli-responsive lipid membrane mesoporous silica nanoparticles (HA-PL-MSNs) were designed and assembled, with the chemotherapeutic agent doxorubicin (DOX) as the model drug. HA-PL-MSNs exhibited a well-defined mesostructure covered by lipid bilayer and part...

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Detalles Bibliográficos
Autores principales: Wang, Zhihui, Tian, Yongfeng, Zhang, Hua, Qin, Yanmei, Li, Dong, Gan, Li, Wu, Fanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147400/
https://www.ncbi.nlm.nih.gov/pubmed/27980406
http://dx.doi.org/10.2147/IJN.S117184