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Using hyaluronic acid-functionalized pH stimuli-responsive mesoporous silica nanoparticles for targeted delivery to CD44-overexpressing cancer cells
In this study, novel hyaluronic acid-pH stimuli-responsive lipid membrane mesoporous silica nanoparticles (HA-PL-MSNs) were designed and assembled, with the chemotherapeutic agent doxorubicin (DOX) as the model drug. HA-PL-MSNs exhibited a well-defined mesostructure covered by lipid bilayer and part...
Autores principales: | Wang, Zhihui, Tian, Yongfeng, Zhang, Hua, Qin, Yanmei, Li, Dong, Gan, Li, Wu, Fanhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147400/ https://www.ncbi.nlm.nih.gov/pubmed/27980406 http://dx.doi.org/10.2147/IJN.S117184 |
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