Cargando…
Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway
Fluorouracil (5-FU) is the most commonly used chemotherapeutic agent for gastric cancer (GC). However, the occurrence of resistance to 5-FU treatment poses a major problem for its clinical efficacy. In this study, we found that the NFκB-signaling pathway can mediate 5-FU resistance in GC cells. We d...
Autores principales: | Kang, Yanting, Hu, Wanle, Bai, Encheng, Zheng, Hailun, Liu, Zhiguo, Wu, Jianzhang, Jin, Rong, Zhao, Chengguang, Liang, Guang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147405/ https://www.ncbi.nlm.nih.gov/pubmed/27980427 http://dx.doi.org/10.2147/OTT.S118272 |
Ejemplares similares
-
L61H46 shows potent efficacy against human pancreatic cancer through inhibiting STAT3 pathway
por: Bai, Encheng, et al.
Publicado: (2018) -
Curcumin Analog Pentagamavunon-1 (PGV-1) Sensitizes Widr Cells to 5-Fluorouracil through Inhibition of NF-κB Activation
por: Meiyanto, Edy, et al.
Publicado: (2018) -
Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer
por: Shi, Lingyi, et al.
Publicado: (2017) -
Curcumin Enhances the Anticancer Effect Of 5-fluorouracil against Gastric Cancer through Down-Regulation of COX-2 and NF- κB Signaling Pathways
por: Yang, Hongru, et al.
Publicado: (2017) -
Nifuratel, a novel STAT3 inhibitor with potent activity against human gastric cancer cells
por: Zheng, Hailun, et al.
Publicado: (2017)