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PEG-b-PCL polymeric nano-micelle inhibits vascular angiogenesis by activating p53-dependent apoptosis in zebrafish

Micro/nanoparticles could cause adverse effects on cardiovascular system and increase the risk for cardiovascular disease-related events. Nanoparticles prepared from poly(ethylene glycol) (PEG)-b-poly(ε-caprolactone) (PCL), namely PEG-b-PCL, a widely studied biodegradable copolymer, are promising ca...

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Detalles Bibliográficos
Autores principales: Zhou, Tian, Dong, Qinglei, Shen, Yang, Wu, Wei, Wu, Haide, Luo, Xianglin, Liao, Xiaoling, Wang, Guixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147414/
https://www.ncbi.nlm.nih.gov/pubmed/27980407
http://dx.doi.org/10.2147/IJN.S112658