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Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag
Recombinant tau protein is widely used to study the biochemical, cellular and pathological aspects of tauopathies, including Alzheimer's disease and frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTPD-17). Pure tau in high yield is a requirement for in vitro evaluation of th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147519/ https://www.ncbi.nlm.nih.gov/pubmed/27663563 http://dx.doi.org/10.1016/j.pep.2016.09.009 |