Utility and Limitations of Using Gene Expression Data to Identify Functional Associations

Gene co-expression has been widely used to hypothesize gene function through guilt-by association. However, it is not clear to what degree co-expression is informative, whether it can be applied to genes involved in different biological processes, and how the type of dataset impacts inferences about...

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Detalles Bibliográficos
Autores principales: Uygun, Sahra, Peng, Cheng, Lehti-Shiu, Melissa D., Last, Robert L., Shiu, Shin-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147789/
https://www.ncbi.nlm.nih.gov/pubmed/27935950
http://dx.doi.org/10.1371/journal.pcbi.1005244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147789/
https://www.ncbi.nlm.nih.gov/pubmed/27935950
http://dx.doi.org/10.1371/journal.pcbi.1005244

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