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Utility and Limitations of Using Gene Expression Data to Identify Functional Associations
Gene co-expression has been widely used to hypothesize gene function through guilt-by association. However, it is not clear to what degree co-expression is informative, whether it can be applied to genes involved in different biological processes, and how the type of dataset impacts inferences about...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147789/ https://www.ncbi.nlm.nih.gov/pubmed/27935950 http://dx.doi.org/10.1371/journal.pcbi.1005244 |