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Alpha Helices Are More Robust to Mutations than Beta Strands
The rapidly increasing amount of data on human genetic variation has resulted in a growing demand to identify pathogenic mutations computationally, as their experimental validation is currently beyond reach. Here we show that alpha helices and beta strands differ significantly in their ability to to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147804/ https://www.ncbi.nlm.nih.gov/pubmed/27935949 http://dx.doi.org/10.1371/journal.pcbi.1005242 |