BRCAness and Prognosis in Triple-Negative Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

BRCAness is defined as the set of traits in which BRCA1 dysfunction, arising from gene mutation, methylation or deletion, results in DNA repair deficiency. In the present study, we addressed BRCAness, therapeutic efficacy, recurrence, and survival in patients with triple negative breast cancer (TNBC...

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Detalles Bibliográficos
Autores principales: Tanino, Hirokazu, Kosaka, Yoshimasa, Nishimiya, Hiroshi, Tanaka, Youko, Minatani, Naoko, Kikuchi, Mariko, Shida, Akiko, Waraya, Mina, Katoh, Hiroshi, Enomoto, Takumo, Sengoku, Norihiko, Kajita, Sabine, Hoffman, Robert M., Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147808/
https://www.ncbi.nlm.nih.gov/pubmed/27935989
http://dx.doi.org/10.1371/journal.pone.0165721

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