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MAP3K19 Is Overexpressed in COPD and Is a Central Mediator of Cigarette Smoke-Induced Pulmonary Inflammation and Lower Airway Destruction

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation and lung inflammation resulting in a progressive decline in lung function whose principle cause is cigarette smoke. MAP3K19 is a novel kinase expressed predominantly by alveolar and interstitial macrophage...

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Detalles Bibliográficos
Autores principales:	Boehme, Stefen A., Franz-Bacon, Karin, Ludka, John, DiTirro, Danielle N., Ly, Tai Wei, Bacon, Kevin B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147866/ https://www.ncbi.nlm.nih.gov/pubmed/27935962 http://dx.doi.org/10.1371/journal.pone.0167169

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