Inhibition of Interleukin-6 Receptor in a Murine Model of Myocardial Ischemia-Reperfusion

BACKGROUND: Interleukin-6 (IL-6) levels are upregulated in myocardial infarction. Recent data suggest a causal role of the IL-6 receptor (IL-6R) in coronary heart disease. We evaluated if IL-6R blockade by a monoclonal antibody (MR16-1) prevents the heart from adverse left ventricular remodeling in...

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Detalles Bibliográficos
Autores principales: Hartman, Minke H. T., Vreeswijk-Baudoin, Inge, Groot, Hilde E., van de Kolk, Kees W. A., de Boer, Rudolf A., Mateo Leach, Irene, Vliegenthart, Rozemarijn, Sillje, Herman H. W., van der Harst, Pim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147868/
https://www.ncbi.nlm.nih.gov/pubmed/27936014
http://dx.doi.org/10.1371/journal.pone.0167195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147868/
https://www.ncbi.nlm.nih.gov/pubmed/27936014
http://dx.doi.org/10.1371/journal.pone.0167195

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