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Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil

Fibropapillomatosis (FP) is a neoplastic disease that affects marine turtles worldwide, especially green sea turtles (Chelonia mydas). FP tumors can develop on the body surface of marine turtles and also internally in the oral cavity and viscera. Depending on their quantity, size and anatomical dist...

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Detalles Bibliográficos
Autores principales: Rossi, Silmara, Sánchez-Sarmiento, Angélica María, Vanstreels, Ralph Eric Thijl, dos Santos, Robson Guimarães, Prioste, Fabiola Eloisa Setim, Gattamorta, Marco Aurélio, Grisi-Filho, José Henrique Hildebrand, Matushima, Eliana Reiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147950/
https://www.ncbi.nlm.nih.gov/pubmed/27936118
http://dx.doi.org/10.1371/journal.pone.0167632
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author Rossi, Silmara
Sánchez-Sarmiento, Angélica María
Vanstreels, Ralph Eric Thijl
dos Santos, Robson Guimarães
Prioste, Fabiola Eloisa Setim
Gattamorta, Marco Aurélio
Grisi-Filho, José Henrique Hildebrand
Matushima, Eliana Reiko
author_facet Rossi, Silmara
Sánchez-Sarmiento, Angélica María
Vanstreels, Ralph Eric Thijl
dos Santos, Robson Guimarães
Prioste, Fabiola Eloisa Setim
Gattamorta, Marco Aurélio
Grisi-Filho, José Henrique Hildebrand
Matushima, Eliana Reiko
author_sort Rossi, Silmara
collection PubMed
description Fibropapillomatosis (FP) is a neoplastic disease that affects marine turtles worldwide, especially green sea turtles (Chelonia mydas). FP tumors can develop on the body surface of marine turtles and also internally in the oral cavity and viscera. Depending on their quantity, size and anatomical distribution, these tumors can interfere with hydrodynamics and the ability to feed, hence scoring systems have been proposed in an attempt to quantify the clinical manifestation of FP. In order to establish a new scoring system adapted to geographic regions, we examined 214 juvenile green sea turtles with FP caught or rescued at Brazilian feeding areas, counted their 7466 tumors and classified them in relation to their size and anatomical distribution. The patterns in quantity, size and distribution of tumors revealed interesting aspects in the clinical manifestation of FP in specimens studied in Brazil, and that FP scoring systems developed for other areas might not perform adequately when applied to sea turtles on the Southwest Atlantic Ocean. We therefore propose a novel method to evaluate the clinical manifestation of FP: fibropapillomatosis index (FPI) that provides the Southwest Atlantic fibropapillomatosis score (FPS(SWA)). In combination, these indexing and scoring systems allow for a more objective, rapid and detailed evaluation of the severity of FP in green sea turtles. While primarily designed for the clinical manifestation of FP currently witnessed in our dataset, this index and the score system can be adapted for other areas and compare the characteristics of the disease across regions. In conclusion, scoring systems to classify the severity of FP can assist our understanding on the environmental factors that modulate its development and its impacts on the individual and population health of green sea turtles.
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spelling pubmed-51479502016-12-28 Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil Rossi, Silmara Sánchez-Sarmiento, Angélica María Vanstreels, Ralph Eric Thijl dos Santos, Robson Guimarães Prioste, Fabiola Eloisa Setim Gattamorta, Marco Aurélio Grisi-Filho, José Henrique Hildebrand Matushima, Eliana Reiko PLoS One Research Article Fibropapillomatosis (FP) is a neoplastic disease that affects marine turtles worldwide, especially green sea turtles (Chelonia mydas). FP tumors can develop on the body surface of marine turtles and also internally in the oral cavity and viscera. Depending on their quantity, size and anatomical distribution, these tumors can interfere with hydrodynamics and the ability to feed, hence scoring systems have been proposed in an attempt to quantify the clinical manifestation of FP. In order to establish a new scoring system adapted to geographic regions, we examined 214 juvenile green sea turtles with FP caught or rescued at Brazilian feeding areas, counted their 7466 tumors and classified them in relation to their size and anatomical distribution. The patterns in quantity, size and distribution of tumors revealed interesting aspects in the clinical manifestation of FP in specimens studied in Brazil, and that FP scoring systems developed for other areas might not perform adequately when applied to sea turtles on the Southwest Atlantic Ocean. We therefore propose a novel method to evaluate the clinical manifestation of FP: fibropapillomatosis index (FPI) that provides the Southwest Atlantic fibropapillomatosis score (FPS(SWA)). In combination, these indexing and scoring systems allow for a more objective, rapid and detailed evaluation of the severity of FP in green sea turtles. While primarily designed for the clinical manifestation of FP currently witnessed in our dataset, this index and the score system can be adapted for other areas and compare the characteristics of the disease across regions. In conclusion, scoring systems to classify the severity of FP can assist our understanding on the environmental factors that modulate its development and its impacts on the individual and population health of green sea turtles. Public Library of Science 2016-12-09 /pmc/articles/PMC5147950/ /pubmed/27936118 http://dx.doi.org/10.1371/journal.pone.0167632 Text en © 2016 Rossi et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Rossi, Silmara
Sánchez-Sarmiento, Angélica María
Vanstreels, Ralph Eric Thijl
dos Santos, Robson Guimarães
Prioste, Fabiola Eloisa Setim
Gattamorta, Marco Aurélio
Grisi-Filho, José Henrique Hildebrand
Matushima, Eliana Reiko
Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil
title Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil
title_full Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil
title_fullStr Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil
title_full_unstemmed Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil
title_short Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil
title_sort challenges in evaluating the severity of fibropapillomatosis: a proposal for objective index and score system for green sea turtles (chelonia mydas) in brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147950/
https://www.ncbi.nlm.nih.gov/pubmed/27936118
http://dx.doi.org/10.1371/journal.pone.0167632
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