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Kinase Screening in Pichia pastoris Identified Promising Targets Involved in Cell Growth and Alcohol Oxidase 1 Promoter (P(AOX1)) Regulation
As one of the most commonly used eukaryotic recombinant protein expression systems, P. pastoris relies heavily on the AOX1 promoter (P(AOX1)), which is strongly induced by methanol but strictly repressed by glycerol and glucose. However, the complicated signaling pathways involved in P(AOX1) regulat...
Autores principales: | Shen, Wei, Kong, Chuixing, Xue, Ying, Liu, Yiqi, Cai, Menghao, Zhang, Yuanxing, Jiang, Tianyi, Zhou, Xiangshan, Zhou, Mian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5147967/ https://www.ncbi.nlm.nih.gov/pubmed/27936065 http://dx.doi.org/10.1371/journal.pone.0167766 |
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