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Molecular Evolution of PTEN Pseudogenes in Mammals

Phosphatase and tensin homolog (PTEN) is a tumor-suppressor gene. PTEN pseudogene (PTENp) acts as an endogenous RNA, which regulates its parental gene by competitively binding to the 3’ UTR of PTEN gene in the human. Despite the importance of this pseudogene, little is known about the molecular evol...

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Detalles Bibliográficos
Autores principales: Tang, Jingsi, Ning, Ruihong, Zeng, Bo, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148010/
https://www.ncbi.nlm.nih.gov/pubmed/27936183
http://dx.doi.org/10.1371/journal.pone.0167851

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