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Endothelial-Mesenchymal Transition in Vascular Calcification of Ins2(Akita/+) Mice

Endothelial-mesenchymal transition (EndMT) drives endothelium to contribute to normal development and disease processes. Here, we report that EndMTs occur in the diabetic endothelium of Ins2(Akita/wt) mouse, and show that induction of sex determining region Y-box 2 (Sox2) is a mediator of excess BMP...

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Detalles Bibliográficos
Autores principales:	Guihard, Pierre J., Yao, Jiayi, Blazquez-Medela, Ana M., Iruela-Arispe, Luisa, Boström, Kristina I., Yao, Yucheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148029/ https://www.ncbi.nlm.nih.gov/pubmed/27936229 http://dx.doi.org/10.1371/journal.pone.0167936

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