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Two Isoforms of Yersinia pestis Plasminogen Activator Pla: Intraspecies Distribution, Intrinsic Disorder Propensity, and Contribution to Virulence
It has been shown previously that several endemic Y. pestis isolates with limited virulence contained the I259 isoform of the outer membrane protease Pla, while the epidemic highly virulent strains possessed only the T259 Pla isoform. Our sequence analysis of the pla gene from 118 Y. pestis subsp. m...
Autores principales: | Dentovskaya, Svetlana V., Platonov, Mikhail E., Svetoch, Tat’yana E., Kopylov, Pavel Kh., Kombarova, Tat’yana I., Ivanov, Sergey A., Shaikhutdinova, Rima Z., Kolombet, Lyubov’ V., Chauhan, Sadhana, Ablamunits, Vitaly G., Motin, Vladimir L., Uversky, Vladimir N., Anisimov, Andrey P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148098/ https://www.ncbi.nlm.nih.gov/pubmed/27936190 http://dx.doi.org/10.1371/journal.pone.0168089 |
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