Mechanism of cargo-directed Atg8 conjugation during selective autophagy

Selective autophagy is mediated by cargo receptors that link the cargo to the isolation membrane via interactions with Atg8 proteins. Atg8 proteins are localized to the membrane in an ubiquitin-like conjugation reaction, but how this conjugation is coupled to the presence of the cargo is unclear. He...

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Detalles Bibliográficos
Autores principales: Fracchiolla, Dorotea, Sawa-Makarska, Justyna, Zens, Bettina, de Ruiter, Anita, Zaffagnini, Gabriele, Brezovich, Andrea, Romanov, Julia, Runggatscher, Kathrin, Kraft, Claudine, Zagrovic, Bojan, Martens, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148612/
https://www.ncbi.nlm.nih.gov/pubmed/27879200
http://dx.doi.org/10.7554/eLife.18544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148612/
https://www.ncbi.nlm.nih.gov/pubmed/27879200
http://dx.doi.org/10.7554/eLife.18544

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