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Mechanism of cargo-directed Atg8 conjugation during selective autophagy
Selective autophagy is mediated by cargo receptors that link the cargo to the isolation membrane via interactions with Atg8 proteins. Atg8 proteins are localized to the membrane in an ubiquitin-like conjugation reaction, but how this conjugation is coupled to the presence of the cargo is unclear. He...
Autores principales: | Fracchiolla, Dorotea, Sawa-Makarska, Justyna, Zens, Bettina, de Ruiter, Anita, Zaffagnini, Gabriele, Brezovich, Andrea, Romanov, Julia, Runggatscher, Kathrin, Kraft, Claudine, Zagrovic, Bojan, Martens, Sascha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148612/ https://www.ncbi.nlm.nih.gov/pubmed/27879200 http://dx.doi.org/10.7554/eLife.18544 |
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