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Correction: Prospective pilot study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures: long-term outcomes
Background and study aims: Background and study aims: Temporary placement of a fully covered self-expandable metal stent (FCSEMS) has recently emerged as a treatment option for pancreatic duct strictures due to chronic pancreatitis refractory to conventional plastic stenting. However, there are no d...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
© Georg Thieme Verlag KG
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148627/ https://www.ncbi.nlm.nih.gov/pubmed/27966674 http://dx.doi.org/10.1055/s-0042-121547 |
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author | Matsubara, Saburo Sasahira, Naoki Isayama, Hiroyuki Takahara, Naminatsu Mizuno, Suguru Kogure, Hirofumi Yamamoto, Natsuyo Nakai, Yousuke Tada, Minoru Koike, Kazuhiko |
author_facet | Matsubara, Saburo Sasahira, Naoki Isayama, Hiroyuki Takahara, Naminatsu Mizuno, Suguru Kogure, Hirofumi Yamamoto, Natsuyo Nakai, Yousuke Tada, Minoru Koike, Kazuhiko |
author_sort | Matsubara, Saburo |
collection | PubMed |
description | Background and study aims: Background and study aims: Temporary placement of a fully covered self-expandable metal stent (FCSEMS) has recently emerged as a treatment option for pancreatic duct strictures due to chronic pancreatitis refractory to conventional plastic stenting. However, there are no data about long-term outcomes with this therapeutic option. The aims of the current study were to estimate the feasibility, safety, efficacy, and long-term outcomes of temporary FCSEMS placement for refractory pancreatic duct strictures. Patients and methods: This was a prospective, single-center feasibility study. Ten patients with refractory pancreatic duct strictures due to chronic pancreatitis underwent FCSEMS placement for 3 months. We evaluated the rate of recurrent symptoms after stent removal during long-term follow-up, as well as adverse events (AEs). Results: Two patients required early (within 1 week) stent removal because of intolerable pain or pancreatitis. In the remaining 8 patients, the recurrence rate of any symptoms after FCSEMS removal was 63% during 35 months of follow up. The causes of recurrent symptoms were as follows: recurrence of stricture in 2; stent-induced stricture in 1; impaction of pancreatic stones in 1; and development of a pseudocyst in 1. When limited to stricture, the recurrence rate was 38%. Additional endoscopic treatments were required in 4 patients: a second FCSEMS placement in 1; plastic stent (PS) placement in 1; stone extraction in 1; and endoscopic ultrasound–guided pseudocyst drainage in 1. Asymptomatic stent migration occurred in 2 patients. Suppurative pancreatic ductitis due to food impaction in the FCSEMS occurred in 2 patients, and endoscopic pancreatic duct drainage was performed. Stent-induced ductal changes developed in 2 patients and PS treatment was required in 1 patient for pain relief. Conclusion: The FCSEMS appears to be a feasible and potentially effective option for the management of refractory pancreatic duct strictures due to chronic pancreatitis during long-term follow-up. AEs including post-procedure pain, stent-induced ductal changes, migration, and ductitis are issues that need to be resolved. |
format | Online Article Text |
id | pubmed-5148627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | © Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-51486272016-12-12 Correction: Prospective pilot study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures: long-term outcomes Matsubara, Saburo Sasahira, Naoki Isayama, Hiroyuki Takahara, Naminatsu Mizuno, Suguru Kogure, Hirofumi Yamamoto, Natsuyo Nakai, Yousuke Tada, Minoru Koike, Kazuhiko Endosc Int Open Background and study aims: Background and study aims: Temporary placement of a fully covered self-expandable metal stent (FCSEMS) has recently emerged as a treatment option for pancreatic duct strictures due to chronic pancreatitis refractory to conventional plastic stenting. However, there are no data about long-term outcomes with this therapeutic option. The aims of the current study were to estimate the feasibility, safety, efficacy, and long-term outcomes of temporary FCSEMS placement for refractory pancreatic duct strictures. Patients and methods: This was a prospective, single-center feasibility study. Ten patients with refractory pancreatic duct strictures due to chronic pancreatitis underwent FCSEMS placement for 3 months. We evaluated the rate of recurrent symptoms after stent removal during long-term follow-up, as well as adverse events (AEs). Results: Two patients required early (within 1 week) stent removal because of intolerable pain or pancreatitis. In the remaining 8 patients, the recurrence rate of any symptoms after FCSEMS removal was 63% during 35 months of follow up. The causes of recurrent symptoms were as follows: recurrence of stricture in 2; stent-induced stricture in 1; impaction of pancreatic stones in 1; and development of a pseudocyst in 1. When limited to stricture, the recurrence rate was 38%. Additional endoscopic treatments were required in 4 patients: a second FCSEMS placement in 1; plastic stent (PS) placement in 1; stone extraction in 1; and endoscopic ultrasound–guided pseudocyst drainage in 1. Asymptomatic stent migration occurred in 2 patients. Suppurative pancreatic ductitis due to food impaction in the FCSEMS occurred in 2 patients, and endoscopic pancreatic duct drainage was performed. Stent-induced ductal changes developed in 2 patients and PS treatment was required in 1 patient for pain relief. Conclusion: The FCSEMS appears to be a feasible and potentially effective option for the management of refractory pancreatic duct strictures due to chronic pancreatitis during long-term follow-up. AEs including post-procedure pain, stent-induced ductal changes, migration, and ductitis are issues that need to be resolved. © Georg Thieme Verlag KG 2016-11 /pmc/articles/PMC5148627/ /pubmed/27966674 http://dx.doi.org/10.1055/s-0042-121547 Text en © Thieme Medical Publishers |
spellingShingle | Matsubara, Saburo Sasahira, Naoki Isayama, Hiroyuki Takahara, Naminatsu Mizuno, Suguru Kogure, Hirofumi Yamamoto, Natsuyo Nakai, Yousuke Tada, Minoru Koike, Kazuhiko Correction: Prospective pilot study of fully covered self-expandable metal stents for refractory benign pancreatic duct strictures: long-term outcomes |
title | Correction: Prospective pilot study of fully covered self-expandable metal
stents for refractory benign pancreatic duct strictures: long-term
outcomes |
title_full | Correction: Prospective pilot study of fully covered self-expandable metal
stents for refractory benign pancreatic duct strictures: long-term
outcomes |
title_fullStr | Correction: Prospective pilot study of fully covered self-expandable metal
stents for refractory benign pancreatic duct strictures: long-term
outcomes |
title_full_unstemmed | Correction: Prospective pilot study of fully covered self-expandable metal
stents for refractory benign pancreatic duct strictures: long-term
outcomes |
title_short | Correction: Prospective pilot study of fully covered self-expandable metal
stents for refractory benign pancreatic duct strictures: long-term
outcomes |
title_sort | correction: prospective pilot study of fully covered self-expandable metal
stents for refractory benign pancreatic duct strictures: long-term
outcomes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148627/ https://www.ncbi.nlm.nih.gov/pubmed/27966674 http://dx.doi.org/10.1055/s-0042-121547 |
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