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CMKLR1 activation ex vivo does not increase proportionally to serum total chemerin in obese humans

Prochemerin is the inactive precursor of the adipokine chemerin. Proteolytic processing is obligatory for the conversion of prochemerin into active chemerin and subsequent regulation of cellular processes via the chemokine-like receptor 1 (CMKLR1). Elevated plasma or serum chemerin concentrations an...

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Detalles Bibliográficos
Autores principales: Toulany, Jay, Parlee, Sebastian D, Sinal, Christopher J, Slayter, Kathryn, McNeil, Shelly, Goralski, Kerry B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5148798/
https://www.ncbi.nlm.nih.gov/pubmed/27881447
http://dx.doi.org/10.1530/EC-16-0065